Department of Labor filing

Denali Therapeutics 401(k) plan

DENALI THERAPEUTICS 401(K) PLAN · For the plan year ended Dec 31, 2024

Spot something wrong?
Latest public filing 2024 · received Sep 30, 2025

Plan summary

Start with the match, vesting, and fees

Strong

This looks strong based on public filing history. Keep checking the source links because plan rules can change.

Why: The current match still needs a dated source. Vesting is not confirmed yet. The latest filing also shows more employer money than most similar plans.

90Plan health
from public filings
See what drives the plan health score
Employer contributions versus peers86/10030% of the full model
Lower reported administrative cost100/10020% of the full model
Active-participant trend46/10010% of the full model
Net-asset trend100/10010% of the full model
Participant-loan burden100/10010% of the full model
Reported compliance signals100/10010% of the full model
Filing completeness100/10010% of the full model

Published only when at least four measures and half of the model weight are available. Missing information is excluded rather than scored as zero.

Employer matchAsk for the formula

This is the first number to confirm: the match rate, required employee contribution, annual cap, and any true-up.

Value at $100,000 of payDepends on the match

Once the formula is known, this converts the headline benefit into estimated annual dollars.

When the money is yoursAsk about vesting

Vesting decides how much employer money you keep if you leave before staying long enough.

Fees paid by employeesAsk for fee disclosure

The key document is the participant fee disclosure, especially fund expense ratios and account charges.

Investment menuAsk for fund lineup

Look for low-cost index funds, target-date funds, stable-value or bond options, and any brokerage window.

When you can joinAsk about eligibility

Eligibility tells you when contributions and employer money can start after hire.

Automatic enrollmentAsk if automatic

Automatic enrollment and auto-increase features usually help more employees save consistently.

Roth 401(k)Ask if offered

Roth availability matters if you want after-tax contributions inside the workplace plan.

Employer money vs. similar plans86th percentile

Up 8.8% over the filing history shown.

Current terms to confirm: vesting, employee fees, investment choices, eligibility, automatic enrollment, Roth availability

These details are often kept in employee-only plan documents. We show them when there is a dated source clear enough to trust.

Before you enroll: confirm the match, vesting schedule, waiting period, and fees in the current plan documents. The filing history shows how the plan itself has changed.

Keep in mind: public filings do not show your personal investment returns. Missing information does not count against the plan. Today’s benefit rules require a current plan document.

Need the raw filing detail?

The key takeaways are above. Open the full record when you want every number and source note.

Filing comparison · 202490out of 100 among similar-size plans in the same industry when enough peers exist

How this filing compares

Reported employer contributions86th percentileTypical peer $3,137 · based on 5,509 comparable plans
Lower reported administrative expense100th percentileTypical peer $173 · based on 5,672 comparable plans

This comparison uses historical filing figures. It does not compare current match formulas, vesting, investments, or employee fees.

Peer-group method: industry size. The comparison used the most specific peer group with enough valid filings.

The short version

What employees should know

For the year ended Dec 31, 2024, DENALI THERAPEUTICS INC. reported $2,939,683 in employer contributions across this plan, or $7,170 per active participant. This is the best company-wide filing average available—not a promise of what any one employee receives.

People actively participating410

Down 3.3% across the filing years shown. The filing does not report every employee who was eligible.

Employer money over timeUp 8.8%

Change in employer contributions per active participant.

Plan costs over timeDown 99.5%

Change in reported administrative cost per participant. Fund expenses may be separate.

Peer comparison90/100

Compared with similarly sized plans in the same industry.

What this public record cannot answer

For the current match, vesting rules, eligibility, employee fees, and investment choices, we need a recent plan document. We leave those details blank until we have one.

Money and scale

Contributions, assets, and expenses

These are plan-wide totals. They are not individual account balances.

Employer contributions
$2,939,683
$7,170 per active participant
Participant contributions
$6,481,985
Other contributions
$2,310,263
Amounts not classified as employer or participant contributions
Employer share of contributions
31.2%
Active participants
410
Mid-size plan
Total participants
606
571 at the beginning of the year
Ending assets
$65,717,392
$108,445 per participant
Net-asset change
Up 105.0%
Not the same as investment performance
Beginning net assets
$49,662,877
Ending net assets
$65,717,392
Beginning liabilities
$0
Ending liabilities
$0
Total income
$20,004,774
Total expenses
$3,950,259
Administrative expenses
$14
$0 per active participant
Participant loans
$456,021
0.7% of plan assets

Three-year filing history

How the reported figures changed

Each chart uses the selected public filing for that year. Missing values remain blank rather than becoming zero.

Employer money per active participant
2022
$6,592
2023
$7,270
2024
$7,170
Administrative cost per participant
2022
$5
2023
$3
2024
$0
Active participants
2022
424
2023
442
2024
410
Total plan assets
2022
$32,052,603
2023
$49,662,877
2024
$65,717,392
Participant loans as a share of assets
2022
0.9%
2023
0.8%
2024
0.7%
Detailed filing history
Plan yearEmployer money per active participantActive participantsPlan assets
2024$7,17041065.7M
2023$7,27044249.7M
2022$6,59242432.1M

Changes in plan assets are not the same as investment performance.

Plan health

Loans, late deposits, and other filing disclosures

Participant loans as a share of plan assets
0.7%
Independent accountant’s opinion
Unqualified opinion Code 1
Late participant contributions reported
Not reportedA “yes” needs context and is not, by itself, proof of wrongdoing.
Loan defaults reported
0
Lease defaults reported
0Only a small number of filings report these events.
Nonexempt transactions reported
0
Public plan identifier
463872213-001

Insurance and supporting schedules

Additional arrangements reported

These disclosures add context. They should not be read as a score or a judgment on their own.

Additional paid service providers
2$14 in separately reported direct compensation
Compensation reported as formulas
2The filing describes how compensation is calculated but does not provide a comparable dollar total.

Reported plan details

Identity and filing status

Plan type
Retirement plan
Employer arrangement
Single-employer plan
Plan effective date
Jan 1, 2017
Industry
Professional, scientific, and technical services
Amended filing
No
Final filing for this plan
No
Short plan year
No
401(k) feature reported
Yes
Show DOL characteristic codes2T2S2E2G2J2K2F3D2R

Companies paid by the plans

Service providers named in the latest filings

Amounts are combined when the same provider and role appear in more than one plan. Form 5500 filings do not standardize every provider’s job, so treat the role labels as tentative; the provider name and compensation come directly from the filing.

ProviderPossible roleHow certain?Plan yearDirect compensationIndirect compensation
FIDELITY INVESTMENTS INSTITUTIONALotherTentative2024Not reportedunknown

Current plan terms

Help fill the gap the filing leaves.

If you have a current SPD, fee disclosure, or enrollment guide, you can share it with us. We check the source and date before adding anything to the profile.

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Filing evidence

Open the selected public records

We use the latest valid received filing for each year after resolving amendments and duplicate records. Open the source to check the original filing.

Quick answers

Denali Therapeutics 401(k) questions

What is Denali Therapeutics's 401(k) match?

We have not verified a current match formula yet. The public filing shows total employer contributions, but that is not the same as the match.

How much employer money did Denali Therapeutics report adding?

For 2024, the selected filing reports $2,939,683 in employer contributions, or $7,170 per active participant. This is a plan-level historical figure, not a personal match quote.

What is Denali Therapeutics's 401(k) vesting schedule?

We have not verified the current vesting schedule yet. Ask for the latest SPD or benefits guide before counting employer money as fully yours.

What are Denali Therapeutics's 401(k) fees?

The 2024 filing reports $0 in administrative cost per active participant. Fund expenses and employee-level charges may require a current fee disclosure.

Can I use this page to compare Denali Therapeutics with another job offer?

Yes, as a starting point. Compare the documented match, vesting, eligibility, fees, investments, and the filing history, then confirm the current terms before assigning a dollar value to an offer.

Source evidence

What recent SEC filings may add

These snippets come from official SEC filings connected to the employer. They are useful clues, but we keep them separate from fully reviewed current plan terms.

10-K · filed Feb 26, 2026Denali Therapeutics Inc. — 10-K filed 2026-02-26 ↗
Fees

rlier stages of clinical development, primarily due to the increased size and duration of later-stage clinical trials. 133 Table of Contents General and Administrative General and administrative expenses include personnel related expenses, such as salaries, benefits, travel and stock-based compensation expense, expenses for outside profes…

Eligibility

receive federal reimbursement under the Medicaid or Medicare Part B programs or to be sold directly to U.S. government agencies, the manufacturer must extend discounts to entities eligible to participate in the 340B drug pricing program. The required 340B discount on a given product is calculated based on the AMP and Medicaid rebate amoun…

Filing ACK_ID20250930114245NAL0005471587001
Data sourceDOL Form 5500 bulk data ↗
Filing searchEFAST2 ↗